Starfinder Commonly Misunderstood Rules

[liamfisher]

Thrown weapons other then grenades use Strength to attack. Grenades use Dex.
Saving throws vs crit effects or explode effects are equal to half the item level plus the modifier of the ability used to make the attack.
And I missed this at first, The save DC is reduced by the same amount as any attack penalties suffered during the attack. So range penalties or conditions such as off-target can make it easier for the enemy to make saves.

Edit: This includes the penalty from Deadly Aim.

Grenades do not get deadly aim.  Their damage is listed as a special ability, not as damage like the other weapons 

DEADLY AIM (COMBAT)

Your can strike your enemies’ weak points and deal more damage.
Prerequisites: Base attack bonus +1.
Benefit: When you take the attack or full attack action with weapons (including a Solarian’s Solar Manifestation, but not Spells or other special abilities of any kind), you can take a –2 penalty to your attack rolls. If you do, those attacks deal additional damage equal to half your base attack bonus (minimum 1).

Cover modifies saves, just like in Pathfinder.